Novel ubiquitin-conjugating enzyme variant COP10 composes of a complex

Y. Yanagawa¹, G. Suzuki ^1,2, S. Komatsu³, Y. Saijo1, X.-W. Deng¹

¹Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven CT; ²RIKEN Yokohama Institute, National Institute of Agrobiological Sciences, Yokohama, Japan

COP10 (COnstitutive Photomorphogenesis 10) has been initially identified as a negative regulator of photomorphogenesis in Arabidopsis. Interestingly, COP10 was revealed to be a novel ubiqutin-conjugating enzyme variant, which composed of a complex, named COP10 complex. Here we show the biochemical purification data of the COP10 complex.