Selected Publications
Complete list of publications: [Google Scholar] [Pubmed]
Contributions of the Dachsous intracellular domain to Dachsous-Fat signaling
Tripathi BK, Irvine KD. Contributions of the Dachsous intracellular domain to Dachsous-Fat signaling. Development. 2024 Dec 1;151(23):dev202919.
Competition between myosin II and βH-Spectrin regulates cytoskeletal tension
Ibar, C., Chinthalapudi, K., Heissler, S.M., and Irvine, K.D. 2023. Competition between myosin II and βH-Spectrin regulates cytoskeletal tension. eLife, 12:RP84918.
AJUBA and WTIP can compete with LIMD1 for junctional localization and LATS regulation
Kirichenko, E. and Irvine, K.D. 2022. AJUBA and WTIP can compete with LIMD1 for junctional localization and LATS regulation. microPublication Biology, 10.17912/micropub.biology.000666.
Analysis of the Drosophila Ajuba LIM protein defines functions for distinct LIM domains
Rauskolb, C., Han, A., Kirichenko, E., Ibar, C. and Irvine, K.D. 2022. Analysis of the Drosophila Ajuba LIM protein defines functions for distinct LIM domains. PLoS One, 17, e0269208.
The wing imaginal disc
Tripathi, B. K. and Irvine, K.D. 2022. The wing imaginal disc. Genetics, 220, iyac020
TRIP6 is required for tension at adherens junctions
Venkatramanan, S., Ibar, C. and Irvine, K.D. 2021. TRIP6 is required for tension at adherens junctions. J Cell Science, 134, jcs.247866
Integration of Hippo-YAP signaling with metabolism
Ibar, C. and Irvine, K.D. 2020. Integration of Hippo-YAP signaling with metabolism. Dev Cell, 54, p256-267.
Organization and Function of Tension-dependent Complexes at Adherens Junctions.
Rauskolb, C., Cervantes, E., Madere, F. and Irvine, K.D. 2019. J Cell Science, 132, jcs224063.
Early girl is a novel component of the Fat signaling pathway.
Misra, J.R. and Irvine, K.D. 2019. PLoS Genetics, 15, e1007955.
Oriented cell divisions are not required for Drosophila wing shape.
Zhou, Z. Alégot, H., and Irvine, K.D. 2019. Current Biology, 29, 856-864.
Recruitment of Jub by a-catenin promotes Yki activity and Drosophila wing growth.
Alégot, H., Markosian, C., Rauskolb, C. Yang, J., Kirichenko, E., Wang, Y.-C., and Irvine, K.D. 2019. J Cell Science, 132, jcs222018.
The Dynamics of Hippo Signaling during Drosophila Wing.
Pan, Y., Alégot, H., Rauskolb, C. and Irvine, K.D. 2018. Development, 145, dev165712.
Tension-dependent regulation of mammalian Hippo signaling through LIMD1.
Ibar, C., Kirichenko, E., Keepers, B., Enners, E., Fleisch K. and Irvine, K.D. 2018. J Cell Science, 131, jcs214700.
Vamana couples Fat signaling to the Hippo pathway.
Misra, J.R. and Irvine, K.D. 2016. Dev. Cell 39, 254-266. PMCID: PMC5102026
Differential growth triggers mechanical feedback that elevates Hippo signaling.
Pan, Y., Heemskerk, I., Ibar, C., Shraiman, B. I. and Irvine, K.D. 2016. Proc. Nat. Acad. Sci. USA 113, E6974-E6983 PMCID: PMC5111668
Localization of Hippo Signaling complexes and Warts activation in vivo.
Sun, S., Reddy, B.V.V.G., and Irvine, K.D. 2015. Nature Communications 6, 8402. PMCID: PMC4598633
Coordination of planar cell polarity pathways through Spiny legs.
Ambegaonkar, A.A. and Irvine, K.D. 2015. eLife 4, e09946. PMCID: PMC4764577
Cytoskeletal Tension inhibits Hippo signaling through an Ajuba-Warts complex.
Rauskolb, C., Sun, S., Sun, G., Pan, Y. and Irvine, K.D. 2014. Cell, 158, 143-156. PMCID: PMC4082802
Regulation of YAP by Mechanical Strain through Jnk and Hippo Signaling.
Codelia, V., Sun, G., and Irvine, K.D. 2014. Current Biology, 24, 2012-2017. PMCID: PMC4160395
Ajuba family proteins link JNK to Hippo signaling. Science Signaling 6, ra81.
Sun, G. and Irvine, K.D. 2013. PMCID: PMC3830546
Regulation of Hippo signaling by EGFR-MAPK signaling through Ajuba family proteins.
Reddy, B.V.V.G. and Irvine, K.D. 2013. Dev. Cell 24, 459-471. PMCID: PMC3624988
Propagation of Dachsous-Fat Planar Cell Polarity.
Ambegaonkar, A.A., Pan, G., Mani, M., Feng, Y. and Irvine, K.D. 2012. Current Biology 22, 1302-1308. PMCID: PMC3418676
Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development.
Mao, Y., Mulvaney, J., Zakaria, S., Yu, T., Malanga, K., Allen, S., Basson, M.A., Francis-West, P., and Irvine, K.D. 2011. Development, 138, 947-957. PMCID: PMC3035097
Modulation of Fat-Dachsous binding by the cadherin domain kinase Four-jointed.
Simon, M.A., Xu, A., Ishikawa, H.O. and Irvine, K.D. 2010. Current Biology 20, 811-817. PMCID: PMC2884055
Warts and Yorkie mediate intestinal regeneration by influencing stem cell proliferation.
Staley, B.K. and Irvine, K.D. 2010. Current Biology 20, 1580-1587. PMCID: PMC2955330
Four-jointed is a Golgi kinase that phosphorylates a subset of cadherin domains.
Ishikawa, H.O., Takeuchi, H., Haltiwanger, R.S. and Irvine, K.D. 2008. Science 321, 401-404. PMCID: PMC2562711
Delineation of a Fat tumor suppressor pathway.
Cho, E., Feng, Y., Rauskolb, C., Maitra, S., Fehon, R., and Irvine, K.D. 2006. Nature Genetics 38, 1142-1150.